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1 (one, unit, unity) is a number representing a single or the only entity. 1 is also a numerical digit and represents a single unit of counting or measurement. For example, a line segment of unit length is a line segment of length 1. In conventions of sign where zero is considered neither positive nor negative, 1 is the first and smallest positive integer. It is also sometimes considered the first of the infinite sequence of natural numbers, followed by 2, although by other definitions 1 is the second natural number, following 0.

The fundamental mathematical property of 1 is to be a multiplicative identity, meaning that any number multiplied by 1 equals the same number. Most if not all properties of 1 can be deduced from this. In advanced mathematics, a multiplicative identity is often denoted 1, even if it is not a number. 1 is by convention not considered a prime number; this was not universally accepted until the mid-20th century. Additionally, 1 is the smallest possible difference between two distinct natural numbers.

The unique mathematical properties of the number have led to its unique uses in other fields, ranging from science to sports. It commonly denotes the first, leading, or top thing in a group.

Fifteen or 15 may refer to:

• 15 (number), the natural number following 14 and preceding 16
• one of the years 15 BC, AD 15, 1915, 2015

Sixteen or 16 may refer to:

• 16 (number), the natural number following 15 and preceding 17
• one of the years 16 BC, AD 16, 1916, 2016

24 may refer to:

• 24 (number), the natural number following 23 and preceding 25
• one of the years 24 BC, AD 24, 1924, 2024

Year 300 (CCC) was a leap year starting on Monday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Constantius and Valerius (or, less frequently, year 1053 Ab urbe condita). The denomination 300 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years.

Year 400 (CD) was a leap year starting on Sunday (link will display the full calendar) of the Julian calendar. In the Roman Empire, it was known as the Year of the Consulship of Stilicho and Aurelianus (or, less frequently, year 1153 Ab urbe condita). The denomination 400 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years.

An allergen is a type of antigen that produces an abnormally vigorous immune response in which the immune system fights off a perceived threat that would otherwise be harmless to the body. Such reactions are called allergies.

In technical terms, an allergen is an antigen that is capable of stimulating a type-I hypersensitivity reaction in atopic individuals through immunoglobulin E (IgE) responses. Most humans mount significant Immunoglobulin E responses only as a defense against parasitic infections. However, some individuals may respond to many common environmental antigens. This hereditary predisposition is called atopy. In atopic individuals, non-parasitic antigens stimulate inappropriate IgE production, leading to type I hypersensitivity.

Sensitivities vary widely from one person (or from one animal) to another. A very broad range of substances can be allergens to sensitive individuals.

A design is the concept of or proposal for an object, process, or system. Design refers to something that is or has been intentionally created by a thinking agent, though it is sometimes used to refer to the nature of something – its design. The verb to design expresses the process of developing a design. In some cases, the direct construction of an object without an explicit prior plan may also be considered to be a design (such as arts and crafts). A design is expected to have a purpose within a certain context, usually having to satisfy certain goals and constraints, and to take into account aesthetic, functional, economic, environmental or socio-political considerations. Typical examples of designs include architectural and engineering drawings, circuit diagrams, sewing patterns, and less tangible artefacts such as business process models.

The drum is a member of the percussion group of musical instruments. In the Hornbostel-Sachs classification system, it is a membranophone. Drums consist of at least one membrane, called a drumhead or drum skin, that is stretched over a shell and struck, either directly with the player's hands, or with a percussion mallet, to produce sound. There is usually a resonant head on the underside of the drum. Other techniques have been used to cause drums to make sound, such as the thumb roll. Drums are the world's oldest and most ubiquitous musical instruments, and the basic design has remained virtually unchanged for thousands of years.

Drums may be played individually, with the player using a single drum, and some drums such as the djembe are almost always played in this way. Others are normally played in a set of two or more, all played by one player, such as bongo drums and timpani. A number of different drums together with cymbals form the basic modern drum kit.